First Hill is a neighborhood in Seattle, named for the hill on which it is located. The hill, in turn, is so named for being the first hill one encounters traveling east from downtown Seattle toward Lake Washington. First Hill is bounded on the west by Interstate 5, beyond which is Downtown, on the north by E. Pike and E. Madison Streets, beyond which is Capitol Hill, and on the south by E. Yesler Way, beyond which is the International District. Its eastern limit, beyond which is the Central District, is indeterminate, but has been said to lie anywhere from 12th to 18th Avenues. (The area between 12th and 20th Avenues is also known as Squire Park.)
The hill is also known as "Pill Hill" because, in addition to being the current home of three major health care facilities (Harborview Medical Center, Swedish Medical Center/First Hill, and Virginia Mason Medical Center (four if Swedish Medical Center/Providence, located on 16th Avenue, is included in the neighborhood), as well as the Puget Sound Blood Center, it was also once the location of the Maynard, Seattle General, and Doctors Hospitals (all of which merged into Swedish) as well as Cabrini Hospital.
First Hill has been home to Seattle University, a private Jesuit university, since 1898. Also located on the hill are Northwest School and Seattle Academy of Arts and Sciences--two highly regarded private schools--and the Catholic O'Dea High School, as well as several churches that have become city landmarks: Trinity Episcopal Parish Church, St. James Cathedral, and Seattle First Baptist Church.
Courtesy of Wikipedia.org